Ksilink engaged in EnvironMENTAL

Apr 1, 2022 | Short news

Ksilink proudly takes part of the EC funded EnvironMENTAL consortium.

Want to know more? You are invited to join a series of seminars!

EnvironMENTAL aims at identifying the molecular and neural mechanisms of environmentally-induced mental illness. It integrates expertise from a wide range of scientific disciplines, including neuroscientists, psychiatrists, geo-scientist, climatologists, psychologists, epidemiologists, anthropologists, sociologists, computer scientists, experts in digital interventions as well as non-academic stakeholders. (A more detailed abstract can be found below)

In this framework you are invited to participate in 5 virtual seminars, open for the scientific community, organised by the consortium between April 8th and June 2022, showing how the research approach of the different scientific disciplines will contribute to advance the state of the art of population neuroscience in the environMENTAL project.

Please find below the agenda and video-links to the seminars

Seminar 1: Identification of adverse environmental signatures and their effect on brain and behaviour to be held on Friday, 8. April 2022; 9.00h to 12.00h CET, 16.00h to 21.00h Chinese time.

Zoom Meeting
Meeting ID: 913 134 0607
Passcode: 12345

Follow-up seminars will be hold on

Seminar 2: Characterization of molecular, neurobiological and cognitive mechanisms underlying the brain and behavioural changes related to environmental adversity

Friday, 22. April 2022; 10.00h to 13.00h CET, 17.00h to 22.00h Chinese time.
Organizer: Sylvane Desrivieres, KCL

Seminar 3: Establishment of quantitative neurobiological biomarkers for prediction and stratification of environmentally-related mental illness

Monday, 23. May 2022; 9.00h to 12.00h CET, 16.00h to 21.00h Chinese time.
Organizer: Andre Marquand, Donders Institute

Seminar 4: Development of pharmacological, cognitive and educational interventions targeting molecular and neurobiological mechanisms of environmentally-sensitive symptoms of mental illness.

Friday, 24. June 2022; 9.00h to 12.00h CET, 16.00h to 21.00h Chinese time.
Organizer: Peter Sommer, Ksilink

Seminar 5: Establishing a programme of responsible research and innovation

Tuesday, 5 July from 9.00 to 13.00h CET 05 July from 9.00h to 13.00h CET, 16.00h to 22.00h Chinese time.
Organizer: Bernd Carsten Stahl, DMU

Please circulate this invitation widely among your peers and students.

We will investigate how some of the greatest global environmental challenges, climate change, urbanisation, and psychosocial stress caused by the Covd19-pandemic affect brain health during the lifespan, and develop interventions aimed at prevention and early intervention. Leveraging federated cohort data of over 1 million European citizens and patients enriched with deep phenotyping data form large scale behavioural neuroimaging cohorts, we will identify brain mechanisms related to environmental adversity underlying symptoms of depression, anxiety, stress and substance abuse. By linking population and patient data via geo-location to environmental data derived from remote sensing satellite measures, climate models as well as digital health applications, our interdisciplinary team will develop a neurocognitive model of multimodal environmental influences defined by transdiagnostic symptom groups of mental illness and their brain correlates. We will uncover the molecular mechanisms underlying this model using multi-modal omics analyses, 3D-brain organoid aggregates and virtual brain simulations. This work will provide an integrated perspective for each individual that incorporates the genetic and environmental influences on brain systems and psychopathology and behaviour, across the lifespan and spectrum of functioning, which we will apply to develop risk biomarkers and stratification markers for different disease mechanisms. Based on the mechanistic knowledge generated, we will then identify compounds targeting causal mechanisms of disease and develop in close collaborations with stakeholders adapted digital health interventions using virtual reality that target symptom clusters defined by shared brain mechanisms. Together, this project will lead to the development of objective biomarkers and evidence-based interventions that will significantly improve outcomes of environmentally-related mental illness.

List of environMENTAL partners:

  • Charité (Gunter Schumann, coordinator) Charité DE/FUDAN CN.
  • Freie Universität Berlin FUB DE.
  • Zentralinstitut für Seelische Gesundheit CIMH DE.
  • Universitätsklinikum Schleswig Holstein, Kiel UKSH DE.
  • University of Oslo UiO NO.
  • Oslo Universitetssykehus Hf – Affiliated Entity OUS NO.
  • Universität Potsdam UP DE.
  • RadboudUMC RUMC NL.
  • Institute for Science and Technology Austria ISTA AU.
  • University of Barcelona UB ES.
  • Universitätsklinikum Bonn UBO DE.
  • Life and Brain Bonn LB DE.
  • Ksilink (SME) KL FR.
  • Aix-Marseille Universite AMU FR.
  • Virtual Bodyworks VB ES.
  • Friedrich Schiller University, Jena, Germany.
  • ARTTIC Innovation GmbH AI DE

Associated Partners:

  • Fudan University Shanghai, ISTBI FUDAN CN.
  • King’s College London KCL UK.
  • De Montfort University Leicester DMU UK.
  • Georgia State University; TReNDs Center GSU USA.
  • University of Southern California USC USA.
  • Google Inc. Google USA
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