by Ksil20@Nw-wsite | May 7, 2021
Therapeutic area: Neuromuscular Disorders Disease: Myotonic Dystrophy Type 1 (MD-1) Monogenic inroad: DMPK Cellular Model: Patient derived skeletal muscle cells Project Origin: I-Stem, Cécile Martinat and Prof Marc Peschanski Medical need: MD1 is a type of muscular...
by Ksil20@Nw-wsite | May 6, 2021
Therapeutic area: Muscular Disorders, Cardiomyopathy Disease: Dilated Cardio Myopathy Monogenic inroad: TITIN Cellular Model: Patient-derived cardiomyocytes (ventricular) Project Origin: Technische Universität München, Klinikum rechts der Isar, Prof. Karl-Ludwig...
by Ksil20@Nw-wsite | May 4, 2021
Therapeutic area: CNS, Psychiatric Disorders Disease: Schizophrenia Monogenic inroad: DISC1 Cellular Model: Patient derived glutamatergic neurons Project Origin: ZI Mannheim, Prof. Andreas Meyer-Lindenberg Medical need: Schizophrenia is a chronic and severe mental...
by Ksil20@Nw-wsite | May 1, 2021
Therapeutic area: Oncology Disease: Non Small Cell Lung Cancers (NSCLC) / other cancers Monogenic inroad: Smarca 2 Cellular Model: Patient-derived cell line Project Origin: DKFZ, Prof. Nicolas Gunkel Medical need: SMARCA4 mutations have been identified in a high...
by Ksil20@Nw-wsite | Apr 16, 2021
Therapeutic area: CNS, neurodegenerative disorders Disease: Parkinson’s Disease Monogenic inroad: Alpha Synuclein (SNCA) and LRRK2 (G2019S) Cellular Model: Patient-derived cell lines Project Origin: University of Luxembourg, Prof. Rejko Krüger Medical...
